I've always thought of them as a temporarily-used, additional layer of treatment for a freshwater tank to quickly reduce overwhelmingly high numbers of organisms (disease or algae) suspended in the water column.
It won't necessarily be the cure-all, but would help short-circuit a runaway vicious cycle to allow other treatments to do their work.
In a healthy tank, though, where there should be no big problem with organisms in the water column so it's not doing much for the tank on a daily basis, I'd imagine. In fact, in a healthy tank, you'd be killing off a small number of beneficial bacteria that are traveling around in the water column looking for new places to colonize.
That said, I don't own one and have never used one so I'm really just speculating.